Heat exhaustion use homeopathy


Motion sickness use homeopathy

  • Bryonia: Nausea and faintness on rising up often with irritability. Motion of any kind makes nausea worse.
  • Cocculus: Dizziness and nausea when riding or sitting up with a strong desire to lie down. The symptoms are worse from watching moving objects or from seeing or smelling food and in open air. There may be a desire for cold drinks.
  • Nux vomica: Irritability. Severe nausea, though at times there is difficulty vomiting. There may be an intense headache at the back of the head or over both eyes. The patient feels chilly and can be worse from the smell of food, tobacco, and coffee.
  • Petroleum: Dizziness on rising. Persistent nausea with excessive salivation and stomach pain which is worse from passive motion, like riding in a car. Patient can complain of pain and stiffness in the neck. May feel better lying with the head high and from warmth.
  • Sepia: Painful sensation of emptiness in pit of the stomach accompanies nausea. Faintness. Nausea often better from eating, worse in morning before breakfast.
  • Tabacum: Dizziness on opening the eyes. Incessant nausea that is worse from the smell of tobacco smoke. There can be vomiting on the least motion, and there is often a terrible faint, sinking feeling at pit of stomach. The patient is often very pale and wants the abdomen uncovered as that lessens the nausea and vomiting. Feels better in fresh air.

Article by Lisa Samet


How does homeopathy work

How does Homeopathy work?

One of the reasons homeopathy can be so tricky to grasp is because it requires a leap of understanding of concepts. Concepts which are outside the box of mainstream science. Many people dismiss homeopathy outright because we homeopaths use highly diluted substances of all kinds. How could anything so diluted possibly have any effect on the body? It’s no wonder homeopathy is such an enormous stretch for those steeped in mainstream science.

But here’s the thing. Homeopathy may not happily be acknowledged by the limited orthodox view. However, when we start looking at molecular physics, there are some remarkable discoveries made in recent years. We find that the mysteries of homeopathy look positively tame in comparison. Here’s an article I just found in a very mainstream publication about teleportation. A technology previously residing firmly in the domain of science fiction.

Let’s challenge the statement I hear all too often. The statement that there’s no research behind homeopathy. Well, here’s my excuse to link a website that is a fantastic resource and I’d love an excuse to pop it in. Here is an exhaustive list of quality research in the field of homeopathy, as well as other resources.

But what is Homeopathy? Here’s what I tell my clients

I’m going to start by describing what I tell my clients in our first consultation to give them an idea of what to expect. I usually say to them that I’m going to be asking them a whole lot of questions. Many of which seem to have no relation to the reason why they’ve come in. This gives me an understanding of how that person responds as a whole to their environment, and what kind of triggers they have, whether physical, emotional or mental. We homeopaths recognise that the immune system is not just limited to the physical body, and their symptoms are not isolated entities occurring randomly for no reason.

A homeopath needs to ask many questions

Chronic stress and emotional allergy

For example, have you ever heard of an emotional allergy? A common example is the neighbour’s chronically barking dog. The dog may eventually trigger an extreme reaction of irritation, despair, frustration or even outright fury if you hear just one bark. The stress of that series of reactions may lead to other symptoms if it keeps occurring on a long-term basis. There are many types of stress and a lot of factors involved in the causes of stress. We have become far more aware these days of the link between chronic stress and a compromised immune system. 

How does stress affect your health?

Another example is a recurring issue in a close relationship that might trigger a similar set of feelings to what I described above with the barking dog. These kinds of reactions are very useful to discuss in homeopathy because it helps give us clues about how best to support the whole person in a highly individual way. Everyone has their unique story. Everyone has their patterns of illness, whether it be frequent physical ailments or mental/emotional issues, or both.

So, to put things in a nutshell, we treat the person, not just the symptom, so we don’t refer to a client as ‘the hay fever case.’ We would call them ‘the person with a case of hay fever.’ There is a subtle but vital difference, and it lies at the core of homeopathy to put the person first.

How is this relevant to Homeopathic Treatment?

Moving on for a moment to homeopathic remedies. A full list of homeopathic remedies is theoretically impossible to achieve as there are new remedies always being discovered and the possibilities are endless! There are apparently over 8000 homeopathic remediesin existence these days, each with its own detailed, individual set of characteristics and symptoms that we call a remedy picture. A homeopath’s aim is to be able to match the person’s individual set of symptoms, triggers and personality characteristics, to the closest possible remedy picture from our extensive materia medica. It’s a little like a detective trying to match clues left at a crime scene, to gain a thorough understanding of events leading up to it, in the hopes they might solve the case.

 

There are many names of Homeopathic remedies which help chronic stress

A full list of homeopathic remedies would be endless

To give you an example, if someone came in who was suffering from hay fever which made their eyes sting and tear up as though they’d been chopping up onions, I would consider giving them a homeopathic preparation of onion, called Allium cepa. Allium cepa has its own set of symptoms in its remedy picture, covering far more than just irritated eyes.

Giving a matching homeopathic remedy (which we call the similimum), stimulates the immune system in a very specific way. It’s as though the nudge given by the remedy provides an opportunity for the immune system to get a good, long, hard look at itself in a way it hasn’t done before. This forms the basis of how homeopathy works in the body and its underlying principle – that of like cures like, the concept of which has been in existence for many centuries.

How are Homeopathic remedies made?

I’m going to travel down a different path with you now before talking about how remedies are made – that of data storage. We as a society are familiar with substances storing data. We only have to look at the silicon chip to know that certain minerals hold great capacity for carrying and transmitting information. At present, we need a computer for us to interact with the data stored, but what if this is only a stage until our understanding expands?

Let us, for a moment, open our minds to the possibility that other naturally occurring substances can also store information, in ways that our bodies can instantly recognise. If we can so happily accept the capacity of mineral structures to carry information, why are we so quick to dismiss the one substance that is a basic requirement for every single life form on Earth – water?

The idea that water can store information from a substance it has been exposed to is far from new. The biggest mystery is why the findings of eminent scientist Jacques Benveniste were so vehemently dismissed by orthodox science at the time. Had those findings been embraced, we can only imagine how that thread of technological advances might have benefited our society.

The mechanism as to how water stores the medicinal effects in homeopathic remedies has been the subject of much debate. From the presence of nanoparticles discovered in the remedies to the recent discovery of even more microscopic water structures.The latest wave of research has found that water possesses truly remarkable qualities. Add to that the fact that the most plentiful substance in our bodies is water, so it makes sense, to me at least, why homeopathic remedies can influence a person so quickly and effectively.

What is Hoemopathy? Did you know homeopathic remedies helps chronic stress?

Homeopathic remedies from 100 years ago

The reason why I’m talking about storage of information in water is because homeopathic remedies are prepared in a way that defies current mainstream, materialistic science. The remedies are highly diluted, having gone through a series of dilutions and succussions(vigorous shaking). This somehow causes an imprint of the original substance to remain in the liquid even though none of that physical substance remains. Various research studies have been performed in this field to try to isolate subatomic particles, and so far, these have been quite promising. have a look through the links in the previous paragraph.

This means that if your toddler gets hold of a remedy and eats it all at once, we consider that to be one dose because it’s not the physical amount of pills or liquid ingested that causes the effect. It’s all about the repetition of the dose. It makes me think of those sceptics who stood outside the opera house a few years ago. They ate entire vials of homeopathic remedies in one go. They would likely have seen all kinds of powerful results if they had instead taken two pills twice daily over the course of a couple of weeks until the vials were empty.

There are Homeopathic pharmacies around the world which have a list of natural remedies they manufacture. In Australia we access to all of them.

Homeopathy puts the person first

So, to summarise.

  • Homeopathy is based on a series of concepts that have existed since ancient times, even though it works in a way that defies current mainstream science.
  • Homeopathy also puts the person first, seeing how they interact with their world as a whole, entire being. This allows for support of that person in a thorough and deep-acting way. More than merely focusing on isolated symptoms, and this is especially so in a chronic set of conditions.
  • There are branches of science such as quantum physics which are beginning to find ways to explain the mechanism of homeopathy and how it works, which is very inspiring.

Dengue fever and homeopathy

Top Homeopathic Medicines For Dengue Fever

Homeopathic medicines for dengue fever are very effective . They medicines are made of natural substances , are completely safe with no side effects and have shown effective cure in thousands of dengue cases.

 Eupatorium Perfoliatum- One of the  best Homeopathic Medicines for Dengue Fever

I would rank Eupatorium Perfoliatum as the best Homeopathic medicine for Dengue Fever. The one most important symptom of Dengue Fever when Eupatorium Perfoliatum is indicated and can be of great help is – severe muscle and joint pains with high fever. Eupatorium happens to the most effective homeopathic in curing dengue fever .Homeopathic medicine Eupatorium Perfoliatum is also popularly known as “bone set” as it brings about the quickest relief in severe bone and joint pains in fever. The pain can be present in any bone or it can be generalised in the whole body. The patient may also have general body ache with a feeling as if the whole body is broken. Apart from relieving joint pains, Homeopathic medicine Eupatorium Perfoliatum is also very beneficial in providing relief from severe pain in the eyeballs in Dengue Fever. It helps in recovering from headache with nausea and vomiting too. Mainly the patients requiring this remedy for Dengue have severe chill with shivering and severe body pains . In majority of the cases, sweat brings relief in all the symptoms, with the exception of pain in head.

Eupatorium Perfoliatum as a Preventive Homeopathic Medicine for Dengue.

Although there is no concrete research on the role of Eupatorium as preventive homeopathic medicine for dengue fever it widely used as a prophylaxis for dengue. It is used as its usage is in accordance with homeopathic laws of prophylaxis ( laws stated in homeopathic philosophy suggest that the medicine that is closest in symptom-match to the symptoms of an outbreak can be used as a prophylaxis) . The homeopathic medicine which closely corroborates to the symptoms of Dengue outbreak  is Eupatorium Perfoliatum. It can be used in 30 c potenc  twice daily during an outbreak of Dengue fever .

Gelsemium: Homeopathic medicine for Dengue Fever with weakness and prostration

I would rank This medicine ( Gelsemium ) as number two homeopathic medicine for dengue fever Gelsemium is the best Homeopathic remedy for Dengue Fever patients who experience utmost weakness and prostration. A state of dullness, dizziness and drowsiness is the perfect description to select Gelsemium over other Homeopathic medicines for the treatment of Dengue Fever. The patients seem lethargic and have a desire to lie down in perfect silence without any disturbance. He or she also wants to be quiet and dislikes conversation. The patient experiences chill, but in selecting Homeopathic medicine Gelsemium, the chill is most typically marked in the back and travels up and down the back. Another feature is headache with heaviness of eyes. The headache is mainly present in back portion that in most cases travels up to the forehead and eyes. There is also an absence of thirst in majority of cases.

 Homeopathic Mediicnes for dengue fever when Joint Pains and bodyaches are present

Eupatorium Perfoliatum is the best natural Homeopathic cure for body ache in Dengue Fever. Homeopathic remedies Bryonia Alba and Rhus Tox too are of great help in providing relief from joint pains or general body ache in Dengue Fever. Which of the two best suits the patient depends on the specific individual features. The most specific feature to choose Bryonia Alba is worsening of pains by any movement even in the least degree. This Homeopathic medicine is the best remedy when rest is the main position for relief from pain. Extreme thirst with a dry mouth may be felt along with this specific feature. Rhus Tox is the ideal Homeopathic medicine when a patient experiences relief from pain by movement and worsening of pain by taking rest.

Homeopathic medicines for Dengue Fever when Severe Headache accompanies it

The most significant natural Homeopathic medicines for headache in Dengue Fever are Gelsemium, Belladonna and Eupatorium Perfoliatum. Gelsemium is the best Homeopathic remedy when a Dengue Fever patient experiences pain in back of the head (Occiput). The pain can also travel from back of the head to the forehead or eyes. Heaviness of eyes is also marked with pain in head. Homeopathic medicine Belladona is the best choice when pain is marked in the sides of head (temples). For using Belladona, the pain is very violent and throbbing in nature. Tight binding of head provides relief. Natural Homeopathic medicine Eupatorium Perfoliatum is recommended for Dengue Fever patients when the headache is present in top (vertex) of head. The patient may also vomit along with vertex headache.

Homeopathic medicines Dengue Fever when Nausea and vomiting is present

Along with  Eupatorium I would suggest that for relieving nausea and vomiting in Dengue Fever, Homeopathic remedies  Ipecac and Arsenic Album can be used . Ipecac is a Homeopathic medicine of great help when there is persistent nausea and vomiting. . Arsenic Album is the ideal Homeopathic medicine when nausea gets worse by the smell or sight of food and vomiting gets worse from eating or drinking anything.

Homeopathic medicines for Dengue Hemorrhagic Fever

Although Homeopathic medicines are beneficial in treating Dengue Hemorrhagic Fever, urgent medical advice is advised as such cases can be life-threatening and may need urgent hospitalisation. The main Homeopathic medicines that can help in Dengue Hemorrhagic Fever are China, Ipecac and Arsenic Album. Homeopathic medicine China is of great help when there is bleeding from any mucus membrane along with marked exhaustion. Debility and utmost prostration with haemorrhages is its main indication. When the haemorrhages are accompanied by severe nausea and vomiting, then Ipecac is the most suitable Homeopathic medicine. Arsenic Album is the best Homeopathic medicine when utmost anxiety and restlessness accompany bleeding. The person needing Arsenic Album may also have a fear of death along with anxiety. The thirst for water at very small intervals may also be felt by persons who can greatly benefit from Homeopathic remedy Arsenic Album. Please note that Dengue and Dengue Hemorrhagic can turn into a critical life threatening condition, hence should not be treated only with homeopathic medicines. Hospital supervision of the patient is very essential .


Antibiotics toxic?

Please research

What is Fluoroquinolone Toxicity?

by Author: 13
What happened to me? Why did it feel as if a bomb had exploded within my body and mind?  Why did I go from doing CrossFit to being unable to walk a block? Why did I lose my memory and reading comprehension?  Why was I so anxious and scared?  Why were my tendons so weak and sore?  Why did I suddenly lose my energy, endurance and flexibility?

I knew the short answer to those questions. I had suffered from an adverse reaction to ciprofloxacin, a fluoroquinolone antibiotic, and I had gone through fluoroquinolone toxicity syndrome—a multi-symptom, “mysterious” illness that involves damage to connective tissue (tendons, ligaments, cartilage, fascia, etc.) throughout the body, damage to the nervous systems (central, peripheral and autonomic), and more. Even though I knew why I was sick, I was still left wondering, what does fluoroquinolone toxicity mean?  How do fluoroquinolones damage tendons, muscles, cartilage and nerves?  What, exactly, is #fluoroquinolone toxicity?  What happened in my body?

No doctors that I consulted were able to give me any answers to those questions, so I went digging around myself. Here are some hypotheses for the mechanisms by which fluoroquinolones cause nervous system and musculoskeletal damage that manifests as multi-symptom, often chronic, illness.

Mitochondrial Toxicity

Is fluoroquinolone toxicity syndrome a result of mitochondrial damage? This hypothesis has the most evidence to support it. The FDA noted, in their April 27, 2013 Pharmacovigilance Review, “Disabling Peripheral Neuropathy Associated with Systemic Fluoroquinolone Exposure,” that:

“Ciprofloxacin has been found to affect mammalian topoisomerase II, especially in mitochondria. In vitro studies in drug-treated mammalian cells found that nalidixic acid and ciprofloxacin cause a loss of motichondrial DNA (mtDNA), resulting in a decrease of mitochondrial respiration and an arrest in cell growth. Further analysis found protein-linked double-stranded DNA breaks in the mtDNA from ciprofloxacin-treated cells, suggesting that ciprofloxacin was targeting topoisomerase II activity in the mitochondria.”

It is also noted in an article in Science Translational Medicine entitled “Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative Damage in Mammalian Cells” that fluoroquinolones, and other bactericidal antibiotics, “damage mammalian tissues by triggering mitochondrial release of reactive oxygen species (ROS).” And that “increases in ROS led to DNA, protein, and lipid damage in vitro.”

Mitochondrial damage, and the vicious cycle of damaged mitochondria creating oxidative stress (another name for reactive oxygen species/ROS), which leads to more mitochondrial damage, which leads to more oxidative stress, and so on, and so on, can lead to multi-symptom, chronic illness. It is noted by Doctors Bruce H. Cohen, MD and Deborah R. Gold, MD, in Mitochondrial Cytopathy in Adults:  What we Know So Far, that:

“A problem that has vexed the study of mitochondrial diseases ever since the first reported case (in 1962) is that their manifestations are remarkably diverse. Although the underlying characteristic of all of them is lack of adequate energy to meet cellular needs, they vary considerably from disease to disease and from case to case in their effects on different organ systems, age at onset, and rate of progression, even within families whose members have identical genetic mutations. No symptom is pathognomonic, and no single organ system is universally affected. Although a few syndromes are well-described, any combination of organ dysfunctions may occur.”

Doctors Cohen and Gold go on to say that:

“symptoms (of mitochondrial damage) such as fatigue, muscle pain, shortness of breath, and abdominal pain can easily be mistaken for collagen vascular disease, chronic fatigue syndrome, fibromyalgia, or psychosomatic illness.”

Mitochondrial dysfunction, and ROS overproduction (aka, oxidative stress), are associated with many chronic diseases including Parkinson’s, Alzheimer’s, ALS, autoimmune diseases, cancer, fibromyalgia, chronic fatigue syndrome, autism and more.

Fluoroquinolone toxicity symptoms resemble those of autoimmune diseases, neurodegenerative diseases, and mysterious diseases. On many levels, it makes sense that fluoroquinolone toxicity syndrome is a disease of mitochondrial damage and ensuing oxidative stress. Mitochondrial damage and oxidative stress are almost certainly part of the fluoroquinolone toxicity puzzle.

Recommended reading:

  1. Science Translational Medicine, “Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative Damage in Mammalian Cells”
  2. Journal of Young Pharmacists, “Oxidative Stress Induced by Fluoroquinolones on Treatment for Complicated Urinary Tract Infections in Indian Patients
  3. Molecular Pharmacology, “Delayed Cytotocicity and Cleavage of Mitochondrial DNA in Ciprofloxacin Treated Mammalian Cells

Neurotransmitter Malfunctions in Fluoroquinolone Toxicity

The central nervous system (CNS) symptoms of fluoroquinolone toxicity include depression, anxiety, psychosis, paranoia, severe insomnia, paraesthesia, tinnitus, hypersensitivity to light and sound, tremors and suicidal ideation and tendencies. Many of the CNS symptoms of fluoroquinolone toxicity can be attributed to the effects of fluoroquinolones on GABA receptors. Fluoroquinolones “are known to non-competitively inhibit the activity of the neurotransmitter, GABA, thus decreasing the activation threshold needed for that neuron to generate an impulse.” (source)  Inhibition of GABA-A receptors, as well as activation of NMDA receptors, can lead to the many severe adverse effects of fluoroquinolones on the central nervous system.

Basically, fluoroquinolones do the same thing to GABA neurotransmitters as a protracted benzodiazepine withdrawal. It is noted in “Benzodiazepine tolerance, dependency, and withdrawal syndromes and interactions with fluoroquinolone antimicrobials” that:

“Chronic use of benzodiazepines causes compensatory adaptions which cause GABA receptors to become less sensitive to GABA. On discontinuation of benzodiazepines, withdrawal symptoms typically develop which may persist for weeks or months. Antagonism of the GABA-A receptor is believed to be responsible for the CNS toxicity of fluoroquinolones affecting 1–4% of patients treated. Fluoroquinolones have also been found to inhibit benzodiazepine receptor binding. The results of this small study seem to confirm that adverse reactions to fluoroquinolones occur more frequently in the benzodiazepine-dependent population than the 1–4% seen in the general public and may be severe.”

Those who have gone through benzodiazepine withdrawal can tell you that all aspects of one’s body are affected. It is possible that neurotransmitter dysfunction is at the root of all fluoroquinolone toxicity symptoms—though I strongly suspect that all of the potential theories that I mention in this post work in tandem.

Recommended reading:

  1. Toxicology Mechanisms and Methods, “Ciprofloxacin-induced neurotoxicity: evaluation of possible underlying mechanisms.
  2. British Journal of Clinical Pharmacology, “Neurotoxic effects associated with antibiotic use: management considerations
  3. Pharmacology Weekly, “What is the mechanism by which the fluoroquinolone antibiotics (e.g., ciprofloxacin, gemifloxacin, levofloxacin, moxifloxacin) can increase a patient’s risk for developing a seizure or worsen epilepsy?”

Magnesium Deficiency

Fluoroquinolones deplete intracellular magnesium. Magnesium is necessary for more than 300 enzymatic reactions, it is vital for the synthesis of vitamins, and magnesium depletion can lead to many symptoms of fluoroquinolone toxicity and other chronic diseases. Many people suffering from fluoroquinolone toxicity are helped by supplementing magnesium (in various forms). Studies have indicated that the binding of quinolones to DNA is mediated by magnesium.

The hypothesis that fluoroquinolones deplete intracellular magnesium is well described in the article, “Fluoroquinolone antibiotics and type 2 diabetes mellitus:”

“Fluoroquinolones are broad-spectrum antibiotics derived from nalidixic acid that inhibit bacterial topoisomerases. Although very effective therapeutically, fluoroquinolones have been linked with serious side effects such as tendinopathy, peripheral neuropathy, retinopathy, renal failure, hypertension, and seizures. These effects can be rationalized as resulting from a drug-induced magnesium deficiency, and according to the hypothesis it is not coincidental that they resemble the complications resulting from type 2 and gestational diabetes. There has, moreover, been a history of dysglycemia associated with certain fluoroquinolone antibiotics. Gatifloxacin was withdrawn from clinical use after reports of drug-induced hyperglycemia and other fluoroquinolones have been reported to interfere with glucose homeostasis.”

“The precise mechanism by which fluoroquinolones might induce intracellular magnesium deficiency is unclear. It may involve the metal-chelating properties of the 3-carboxyquinolone substructure that is common to all fluoroquinolone antibiotics and the fact that the 6-fluoro substituent on the pharmacophore gives rise to sufficient lipophilicity that the drugs can dissolve in and penetrate cell membranes. It has been suggested that intracellular fluoroquinolones may exist almost exclusively as the magnesium complex. Diffusion or active transport of such a complex into the extracellular environment would lead to depletion of intracellular magnesium – a process that may be stoichiometric or catalytic and would be only very slowly reversible, if at all. Thus, the effects of fluoroquinolones on intracellular magnesium levels might be considered to be almost cumulative (and it is noteworthy that the side-effects of fluoroquinolone therapy may manifest or persist many months after treatment). Alternatively, it is perhaps possible that fluoroquinolones could affect magnesium metabolism by disruption of renal reabsorption of this electrolyte.”

Recommended reading:

  1. Medical Hypotheses, “Fluoroquinolone antibiotics and type 2 diabetes mellitus
  2. Natural News, “Magnesium Helps Heal Cipro Damage
  3. Proceedings of the National Academy of Sciences of the United States, Biochemistry, “Quinolone Binding to DNA Mediated by Magnesium Ions

Microbiome Destruction

Fluoroquinolones are powerful antibiotics that wreak havoc on the bacteria in the gut. In addition to indiscriminately killing bacteria in the gut of the person who takes a fluoroquinolone, fluoroquinolones have also been shown to induce large amounts of oxidative stress within the gut.

The importance of the microbiome for all areas of health is just now being explored.  An unhealthy microbiome is associated with Parkinson’s, Alzheimer’s, depression, rheumatoid arthritis, diabetes, Crohn’s, and many other diseases. There are many who think that the root of all disease is in the gut.

Destruction of vital bacteria, and the induction of oxidative stress within the gut, could be responsible for the havoc wreaked on the health and well-being of those who take fluoroquinolones.

Recommended reading:

  1. Antimicrobial Agents and Chemotherapy, “The Fluoroquinolone Levofloxacin Triggers the Transcriptional Activation of Iron Transport Genes That Contribute to Cell Death in Streptococcus pneumonia
  2. National Institutes of Health, “Human Microbiome Project
  3. Scientific American, “Think Twice: How the Gut’s ‘Second Brain’ Influences Mood and Well-Being

Epigenetic Changes

Fluoroquinolones are topoisomerase interrupters. The mechanism for Cipro/ciprofloxacin, and all other fluoroquinolone antibiotics is:

“The bactericidal action of ciprofloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV (both Type II topoisomerases), which are required for bacterial DNA replication, transcription, repair, and recombination.”

Topoisomerases are enzymes that are necessary for DNA and RNA transcription.  Topoisomerase interrupting drugs have been found to profoundly affect gene expression.  It may be possible that fluoroquinolones trigger the expression of dormant genes. So, for example, those who have a predisposition toward an autoimmune disease may bring on the autoimmune disease with the fluoroquinolone. Anecdotally, it seems as if any existing weakness a person has is exacerbated by fluoroquinolones.

It is hypothesized in “Epigenetic side-effects of common pharmaceuticals: A potential new field in medicine and pharmacology,” that all adverse reactions to fluoroquinolones are due to epigenetic mechanisms:

“The quinolones are a family of broad-spectrum antibiotics. They inhibit the bacterial DNA gyrase or the topoisomerase IV enzyme, thereby inhibiting DNA replication and transcription. Eukaryotic cells do not contain DNA gyrase or topoisomerase IV, so it has been assumed that quinolones and fluoroquinolones have no effect on human cells, but they have been shown to inhibit eukaryotic DNA polymerase alpha and beta, and terminal deoxynucleotidyl transferase, affect cell cycle progression and function of lymphocytes in vitro, and cause other genotoxic effects. These agents have been associated with a diverse array of side-effects including hypoglycemia, hyperglycemia, dysglycemia, QTc prolongation, torsades des pointes, seizures, phototoxicity, tendon rupture, and pseudomembranous colitis. Cases of persistent neuropathy resulting in paresthesias, hypoaesthesias, dysesthesias, and weakness are quite common. Even more common are ruptures of the shoulder, hand, Achilles, or other tendons that require surgical repair or result in prolonged disability. Interestingly, extensive changes in gene expression were found in articular cartilage of rats receiving the quinolone antibacterial agent ofloxacin, suggesting a potential epigenetic mechanism for the arthropathy caused by these agents. It has also been documented that the incidence of hepatic and dysrhythmic cardiovascular events following use of fluoroquinolones is increased compared to controls, suggesting the possibility of persistent gene expression changes in the liver and heart.”

Fluoroquinolones have been found to deplete mitochondrial DNA, and mitochondria have been found to affect geneexpression.

It is possible that fluoroquinolones are profoundly changing gene expression, and that the adverse effects of fluoroquinolones are a result of altered gene expression.  Fluoroquinolones are, after all, topoisomerase interrupters.

Recommended reading:

  1. Medical Hypotheses, “Epigenetic side-effects of common pharmaceuticals: A potential new field in medicine and pharmacology
  2. Mutation Research, “Ciprofloxacin:  Mammalian DNA Topoisomerase Type II Poison In Vivo
  3. Nature, “Topoisomerases facilitate transcription of long genes linked to autism

Thyroid Harm

The harm that fluoroquinolones do to the thyroid is described well in “Fluoroquinolone Antibiotics and Thyroid Problems: Is there a Connection?” on Hormones Matter.  A more in-depth look at fluoroquinolone induced thyroid problems can be found on FluoroquinoloneThyroid.com.

Please don’t interpret the brevity of this section as a reason to discount it as a possible explanation for fluoroquinolone toxicity syndrome. Thyroid dysfunction can wreak havoc on a person’s health and the deleterious effects of fluoroquinolones on the thyroid are a potential explanation for the multi-symptom, chronic illness of fluoroquinolone toxicity. The articles by JMR on both Hormones Matter and fluoroquinolonethyroid.com explore the relationship thoroughly.

All of the source links in “Fluoroquinolone Antibiotics and Thyroid Problems: Is there a Connection?” on Hormones Matter are recommended.

Post-hepatic Syndrome / Liver Damage

Do fluoroquinolones form poisonous acyl glucuronides that lead to post-hepatic syndrome?

I think that it’s a definite possibility, but I also think that I’m not qualified or able to form a coherent and correct explanation of this hypothesis.  Please ask a biochemist to explain the following articles to you:

  1. Drug Metabolism and Disposition, “Acyl Glucuronidation of Fluoroquinolone Antibiotics by the UDP-Glucuronosyltransferase 1A Subfaminly in the Human Liver Microsomes”. 
  2. Current Drug Metabolism, “Editorial [Hot Topic:Acyl Glucuronides: Mechanistic Role in Drug Toxicity? (Guest Editor: Urs A. Boelsterli)]
  3. BMC Public Health, “Adverse effects of the antimalaria drug, mefloquine: due to primary liver damage with secondary thyroid involvement?”  (Note that mefloquine and fluoroquinolones are cousin drugs – they’re both quinine analogues.)

This is a long, and fairly complex, post. Yet I am leaving out many possible explanations for the causes of fluoroquinolone toxicity. Not even touched on are the possibilities that fluoroquinolone toxicity is a lysosomal disorder, autoimmune disease, fluoride overdose, “leaky gut,” histamine response, mast cell activation, serum sickness, and many other possibilities. I suspect that fluoroquinolone toxicity is a combination of all of the things mentioned above, and in this paragraph, and that there are multiple interactions between all of the biological systems. Fluoroquinolone toxicity is a systemic illness and all bodily systems work together.

Though fluoroquinolones can throw a wrench in our biochemistry, the multiple systems that work together to make us sick can also work together to make us well. We have amazing healing mechanisms that are less-understood than the mechanisms that make us sick (and those are pitifully poorly understood).  Our bodies are a complex and wondrous web.  All of our bodily systems work together perfectly most of the time, and they strive to return to health in every moment of life.

Though there are hundreds of articles about the deleterious effects of fluoroquinolones, the question – What is fluoroquinolone toxicity? – remains unanswered.  Any one of the possibilities mentioned above is complex. Put them all together and, well, comprehension becomes close to impossible.  Luckily, comprehension isn’t required for healing.  But it would be very, very, very nice if some efforts toward understanding adverse reactions to fluoroquinolones were being made.

Post script:  The first post I ever wrote on my site about fluoroquinolone toxicity (www.floxiehope.com) was a post like this one, also entitled, “What is Fluoroquinolone Toxicity?”  You can read it HERE.  The 2015 post above is much more thoughtful, well-researched and, in almost every way, it is better. But the 2013 post on Floxie Hope is interesting in its own right.  It went over what it feels like to go through fluoroquinolone toxicity, and it was written from the perspective of a recent victim of fluoroquinolones, not the perspective of someone who has spent hundreds of hours researching fluoroquinolones. The patient perspective, and noting what fluoroquinolone toxicity feels like is valuable, though I think that the connections made in this 2015 post are more accurate.

Information about Fluoroquinolone Toxicity

Information about the author, and adverse reactions to fluoroquinolone antibiotics (Cipro/ciprofloxacin, Levaquin/levofloxacin, Avelox/moxifloxacin and Floxin/ofloxacin) can be found on Lisa Bloomquist’s site, www.floxiehope.com.


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Glyphosate Found in Childhood Vaccines – EcoWatch

Glyphosate, the active ingredient in Monsanto’s herbicide Roundup has been found in vaccines. Moms Across America received preliminary screening results from
— Read on www.ecowatch.com/glyphosate-vaccines-1999343362.html


Homeopathic research 6,000 pages by dr Iris Bell PHD MD

There is a large and growing body of scientific research in the field of homeopathy. Available papers cover basic science studies (looking at the physical and chemical properties of remedies), pre-clinical studies (looking at the effect of homeopathic remedies on plants and animals), and clinical studies (looking at the effects of homeopathic remedies on humans). Those who try to portray homeopathy in a negative way often argue that there is little scientific research available on the topic.  This claim is false.  Homeopathy has been widely studied for over 200 years.

Dr. Iris Bell M.D., Ph.D.

(University of Arizona College of Medicine)

has compiled the most comprehensive list of research papers available in this field (over 6,000) and made it available to members of the homeopathic community.

We in turn, make it available to you. To view the list, click here: Homeopathic Research 

Finally, here are the first of many well done summaries on research in the field on homeopathy for patients suffering with a variety of ailments. The information in the following articles is intended for informational purposes only. Please remember, if you have any of the conditions mentioned in the research below, it is advisable to seek the advice of a licensed practitioner for treatment options.

Homeopathy for Allergies

Homeopathy and Women’s Health

Homeopathy Can Reduce the Need for Antibiotics in America

Homeopathy for Pain

Homeopathy in Mental Health and Psychiatry

The Use of Homeopathy in European Hospitals


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